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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1990 1
1992 1
1993 3
1994 3
1995 5
1996 13
1997 8
1998 9
1999 15
2000 18
2001 14
2002 4
2003 19
2004 21
2005 24
2006 14
2007 24
2008 23
2009 30
2010 31
2011 24
2012 28
2013 25
2014 26
2015 24
2016 22
2017 16
2018 21
2019 15
2020 22
2021 24
2022 21
2023 12
2024 7

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515 results

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Page 1
The interplay between immunosenescence and age-related diseases.
Barbé-Tuana F, Funchal G, Schmitz CRR, Maurmann RM, Bauer ME. Barbé-Tuana F, et al. Semin Immunopathol. 2020 Oct;42(5):545-557. doi: 10.1007/s00281-020-00806-z. Epub 2020 Aug 3. Semin Immunopathol. 2020. PMID: 32747977 Free PMC article. Review.
Features of accelerated immunosenescence can be identified in adults with chronic inflammatory conditions, such as rheumatoid arthritis, and are predictive of poor clinical outcomes. ...In this review, we discuss how the aging immune system may contribute to the dev …
Features of accelerated immunosenescence can be identified in adults with chronic inflammatory conditions, such as rheumatoid arth …
Rheumatoid arthritis.
Goronzy JJ, Weyand CM. Goronzy JJ, et al. Immunol Rev. 2005 Apr;204:55-73. doi: 10.1111/j.0105-2896.2005.00245.x. Immunol Rev. 2005. PMID: 15790350 Review.
Therapeutic efficacy of depleting B cells or blocking T-cell costimulation in rheumatoid arthritis (RA) has confirmed the critical pathogenic role of adaptive immune responses. ...Senescence of effector CD4(+) T cells is associated with the loss of CD28 and t …
Therapeutic efficacy of depleting B cells or blocking T-cell costimulation in rheumatoid arthritis (RA) has confirmed the crit …
CD28(-) Cells Are Increased in Early Rheumatoid Arthritis and Are Linked With Cytomegalovirus Status.
Thompson C, Davies R, Williams A, Jones G, Choy EHS. Thompson C, et al. Front Med (Lausanne). 2020 May 5;7:129. doi: 10.3389/fmed.2020.00129. eCollection 2020. Front Med (Lausanne). 2020. PMID: 32432117 Free PMC article.
Objective: CD3(+)CD8(+)CD28(-) cells are higher in Rheumatoid Arthritis (RA). The aim of this study was to assess CD3(+)CD8(+)CD28(-) cells in patients with early RA and assess the effects of cytomegalovirus (CMV) seropositivity. ...There is a weak but …
Objective: CD3(+)CD8(+)CD28(-) cells are higher in Rheumatoid Arthritis (RA). The aim of this study was to assess CD3(+ …
CD28 and PTPN22 are associated with susceptibility to rheumatoid arthritis in Egyptians.
Hegab MM, Abdelwahab AF, El-Sayed Yousef AM, Salem MN, El-Baz W, Abdelrhman S, Elshabacy F, Alhefny A, Abouraya W, Ibrahim SM, Ragab G, Rudolph JM. Hegab MM, et al. Hum Immunol. 2016 Jun;77(6):522-6. doi: 10.1016/j.humimm.2016.04.018. Epub 2016 Apr 25. Hum Immunol. 2016. PMID: 27125674
OBJECTIVE: Limited data are available on the genetics of rheumatoid arthritis (RA) in Egyptians. Therefore, we investigated whether the confirmed genetic risk factors for RA in Europeans and/or Asians contribute to RA susceptibility in Egyptians. ...Patients were st …
OBJECTIVE: Limited data are available on the genetics of rheumatoid arthritis (RA) in Egyptians. Therefore, we investigated wh …
Expansions of Cytotoxic CD4(+)CD28(-) T Cells Drive Excess Cardiovascular Mortality in Rheumatoid Arthritis and Other Chronic Inflammatory Conditions and Are Triggered by CMV Infection.
Broadley I, Pera A, Morrow G, Davies KA, Kern F. Broadley I, et al. Front Immunol. 2017 Mar 2;8:195. doi: 10.3389/fimmu.2017.00195. eCollection 2017. Front Immunol. 2017. PMID: 28303136 Free PMC article. Review.
Expansions of cytotoxic CD4(+) T cells characterized by loss of CD28 ("CD4(+)CD28(-) T cells" or "CD4(+)CD28(null) cells") are closely associated with cardiovascular disease (CVD), in particular coronary artery damage. Direct involvement of these cells in dam …
Expansions of cytotoxic CD4(+) T cells characterized by loss of CD28 ("CD4(+)CD28(-) T cells" or "CD4(+)CD28(null) cell …
Yoga maintains Th17/Treg cell homeostasis and reduces the rate of T cell aging in rheumatoid arthritis: a randomized controlled trial.
Gautam S, Kumar R, Kumar U, Kumar S, Luthra K, Dada R. Gautam S, et al. Sci Rep. 2023 Sep 11;13(1):14924. doi: 10.1038/s41598-023-42231-w. Sci Rep. 2023. PMID: 37696876 Free PMC article. Clinical Trial.
The pathogenesis of rheumatoid arthritis (RA) is characterized by a Th17/Treg cell imbalance. ...A total of 64 participants with active RA were randomized into 2 groups, yoga group (n = 32) or non-yoga group (n = 32); that were assessed for disease severity, at base …
The pathogenesis of rheumatoid arthritis (RA) is characterized by a Th17/Treg cell imbalance. ...A total of 64 participants wi …
A link between CD8+CD27-CD28- T cells expressing chemerin chemokine-like receptor 1 and rheumatoid arthritis.
Jeong E, Jung JY, Lee MJ, Kim HA, Yang HY, Kim K, Park S. Jeong E, et al. Clin Exp Rheumatol. 2023 May;41(5):1105-1113. doi: 10.55563/clinexprheumatol/52v1bb. Epub 2022 Oct 4. Clin Exp Rheumatol. 2023. PMID: 36200942
As previously reported, the levels of its ligand, chemerin, are increased in the plasma and synovial fluid of patients with rheumatoid arthritis (RA); hence, we aimed to explore the expression and role of CMKLR1 in the T cells of these patients. ...We found a correl …
As previously reported, the levels of its ligand, chemerin, are increased in the plasma and synovial fluid of patients with rheumatoid …
CD28, CTLA-4 and CCL5 gene polymorphisms in patients with rheumatoid arthritis.
Luterek-Puszyńska K, Malinowski D, Paradowska-Gorycka A, Safranow K, Pawlik A. Luterek-Puszyńska K, et al. Clin Rheumatol. 2017 May;36(5):1129-1135. doi: 10.1007/s10067-016-3496-2. Epub 2016 Dec 17. Clin Rheumatol. 2017. PMID: 27988812
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint destruction caused by infiltrating leukocytes including T cells. ...The aim of this study was to examine the associations between polymorphisms within CD28, CTLA-4, and CCL5 gene …
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint destruction caused by infiltrating leukocytes …
Expression patterns of CD28 and CTLA-4 in early, chronic, and untreated rheumatoid arthritis.
García-Chagollán M, Ledezma-Lozano IY, Hernández-Bello J, Sánchez-Hernández PE, Gutiérrez-Ureña SR, Muñoz-Valle JF. García-Chagollán M, et al. J Clin Lab Anal. 2020 May;34(5):e23188. doi: 10.1002/jcla.23188. Epub 2020 Jan 6. J Clin Lab Anal. 2020. PMID: 31907973 Free PMC article.
BACKGROUND: T-cell activation pathways have been proposed as trigger mechanisms in the pathogenesis of rheumatoid arthritis (RA). CD28 and CTLA-4 play major roles in regulating the stimulatory and inhibitory co-signals in T cells. ...Surface expression of …
BACKGROUND: T-cell activation pathways have been proposed as trigger mechanisms in the pathogenesis of rheumatoid arthritis (R …
HLA-DRB1, IRF5, and CD28 gene polymorphisms in Egyptian patients with rheumatoid arthritis: susceptibility and disease activity.
Said NM, Ezzeldin N, Said D, Ebaid AM, Atef DM, Atef RM. Said NM, et al. Genes Immun. 2021 Jun;22(2):93-100. doi: 10.1038/s41435-021-00134-8. Epub 2021 May 20. Genes Immun. 2021. PMID: 34017081
This study was established to assess the effects of IRF5 rs10488631 and CD28 rs1980422 single-nucleotide polymorphisms (SNPs) and HLA-DRB1 shared epitope (SE) allele on the prognosis and disease activity of rheumatoid arthritis (RA) patients. ...A better resp …
This study was established to assess the effects of IRF5 rs10488631 and CD28 rs1980422 single-nucleotide polymorphisms (SNPs) and HLA …
515 results